HLADQB1 protein (His tag) (80R-3415)

Purified recombinant HLADQB1 protein (His tag)

Synonyms MHC class II antigen DQB1 protein, HLA DQB1 protein, HLA-DQB1 protein
Species Human
Protein Type Recombinant
Applications ELISA, SDS-PAGE, WB

Images

Western blot analysis using HLADQB1 protein (His tag) (80R-3415)

Specifications

Expression System E.coli
Purity > 95% pure
Molecular Weight 28 kDa
Tag/Conjugate His tag
Form & Buffer Supplied in liquid form in PBS buffer

Storage & Safety

Storage Store at 4 deg C in a working aliquot for 1 week. For long term storage, aliquot and freeze at -20 to -80 deg C, avoid repeat freeze/thaw cycles

General Information

Biological Significance HLADQB1 binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class II molecules are generated mostly by degradation of proteins that access the endocytic route, where they are processed by lysosomal proteases and other hydrolases. Exogenous antigens that have been endocytosed by the APC are thus readily available for presentation via MHC II molecules, and for this reason this antigen presentation pathway is usually referred to as exogenous.

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Images

  • Western blot analysis using HLADQB1 protein (His tag) (80R-3415)

Availability: In stock

Price: $210.00
Size: 50 ug
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