HNRNPAB protein (His tag) (80R-3504)
Purified recombinant HNRNPAB protein (His tag)
|Synonyms||Heterogeneous nuclear ribonucleoprotein A/B protein, ABBP1 protein, HNRPAB protein|
Coomassie blue stained SDS-PAGE of HNRNPAB protein (His tag) (80R-3504)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-285 aa: MGSSHHHHHH SSGLVPRGSH MGSMSEAGEE QPMETTGATE NGHEAVPEGE SPAGAGTGAA AGAGGATAAP PSGNQNGAEG DQINASKNEEDAGKMFVGGL SWDTSKKDLK DYFTKFGEVV DCTIKMDPNT GRSRGFGFIL FKDAASVEKV LDQKEHRLDG RVIDPKKAMA MKKDPVKKIF VGGLNPEATE EKIREYFGEF GEIEAIELPM DPKLNKRRGF VFITFKEEEP VKKVLEKKFH TVSGSKCEIK VAQPKEVYQQ QQYGSGGRGNRNRGNRGSGG GGGGGGQGST NYGKSQRRGG HQNNYKPY|
|Purity||> 95% pure|
|Method of Purification||HNRNPAB protein was purified by using conventional chromatography techniques|
|Molecular Weight||33 kDa|
|Form & Buffer||Supplied in liquid form in PBS containing 30% glycerol, 1mM DTT|
Storage & Safety
|Storage||Can be stored at 4 deg C short term (1-2 weeks). For long term storage, aliquot and store at -20 deg C or -70 deg C. Avoid repeated freezing and thawing cycles.|
|Biological Significance||HNRNPAB belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are produced by RNA polymerase II and are components of the heterogeneous nuclear RNA (hnRNA) complexes. They are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. HNRNPAB, which binds to one of the components of the multiprotein editosome complex, has two repeats of quasi-RRM (RNA recognition motif) domains that bind to RNAs.|
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