HNRNPAB protein (His tag) (80R-3504)

Purified recombinant HNRNPAB protein (His tag)

Synonyms Heterogeneous nuclear ribonucleoprotein A/B protein, ABBP1 protein, HNRPAB protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

Coomassie blue stained SDS-PAGE of HNRNPAB protein (His tag) (80R-3504)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 1-285 aa: MGSSHHHHHH SSGLVPRGSH MGSMSEAGEE QPMETTGATE NGHEAVPEGE SPAGAGTGAA AGAGGATAAP PSGNQNGAEG DQINASKNEEDAGKMFVGGL SWDTSKKDLK DYFTKFGEVV DCTIKMDPNT GRSRGFGFIL FKDAASVEKV LDQKEHRLDG RVIDPKKAMA MKKDPVKKIF VGGLNPEATE EKIREYFGEF GEIEAIELPM DPKLNKRRGF VFITFKEEEP VKKVLEKKFH TVSGSKCEIK VAQPKEVYQQ QQYGSGGRGNRNRGNRGSGG GGGGGGQGST NYGKSQRRGG HQNNYKPY
Expression System E.coli
Purity > 95% pure
Method of Purification HNRNPAB protein was purified by using conventional chromatography techniques
Molecular Weight 33 kDa
Tag/Conjugate His tag
Form & Buffer Supplied in liquid form in PBS containing 30% glycerol, 1mM DTT
Concentration 250 ug/ml

Storage & Safety

Storage Can be stored at 4 deg C short term (1-2 weeks). For long term storage, aliquot and store at -20 deg C or -70 deg C. Avoid repeated freezing and thawing cycles.

General Information

Biological Significance HNRNPAB belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are produced by RNA polymerase II and are components of the heterogeneous nuclear RNA (hnRNA) complexes. They are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. HNRNPAB, which binds to one of the components of the multiprotein editosome complex, has two repeats of quasi-RRM (RNA recognition motif) domains that bind to RNAs.

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Images

  • Coomassie blue stained SDS-PAGE of HNRNPAB protein (His tag) (80R-3504) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: $365.00
Size: 50 ug
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