Homer 1 protein (His tag) (80R-1146)
Purified recombinant Human Homer 1 protein
|Synonyms||, HOMER 1B protein, neuronal immediate early gene protein, HOMER1B protein, Homer 1 protein, Homer protein homolog 1 HOMER 1A protein, SYN47 protein, HOMER1 protein, HOMER 1C protein, HOMER protein, Homer protein, Ves 1 protein, Homer protein homolog 1 protein, 1 protein, HOMER1A protein, HOMER1C protein|
Coomassie Blue stained SDS-PAGE of Homer 1 protein (His tag) (80R-1146)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-354 amino acids: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMGE QPIFSTRAHV FQIDPNTKKN WVPTSKHAVT VSYFYDSTRN VYRIISLDGS KAIINSTITP NMTFTKTSQK FGQWADSRAN TVYGLGFSSE HHLSKFAEKF QEFKEAARLA KEKSQEKMEL TSTPSQESAG GDLQSPLTPE SINGTDDERT PDVTQNSEPR AEPTQNALPF SHSSAISKHW EAELATLKGN NAKLTAALLE STANVKQWKQ QLAAYQEEAE RLHKRVTELE CVSSQANAVH THKTELNQTI QELEETLKLK EEEIERLKQE IDNARELQEQ RDSLTQKLQE VEIRNKDLEG QLSDLEQRLE KSQNEQEAFR NNLKTLLEIL DGKIFELTEL RDNLAKLLEC S|
|Purity||> 90% pure|
|Molecular Weight||44.5 kDa (391 aa), confirmed by MALDI-TOF.|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 0.1M NaCl, 20% glycerol, and 1mM DTT.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||Homer 1 (Homer protein homolog 1) belongs to Homer family of proteins that regulate signal transduction through, and the trafficking of glutamate receptors as well as maintain and regulate extracellular glutamate levels in corticolimbic brain regions. The Homer 1 is enriched at excitatory synapses and binds group 1 metabotropic glutamate receptors (mGluRs). Recombinant Homer 1 protein was expressed in E. coli and purified by using conventional chromatography techniques.|
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