Hsp27 antibody (10R-8577)

Mouse monoclonal Hsp27 antibody

Synonyms Monoclonal Hsp27 antibody, Anti-Hsp27 antibody, HSPB1 antibody, heat shock 27kDa protein 1 antibody, 25 kDa heat shock protein antibody, 25 kDa IAP antibody, 27kDa antibody, 28 kDa heat shock protein antibody, actin polymerization inhibitor antibody, BOS_22984 antibody, CMT2F antibody, estrogen-regulated 24 kDa protein antibody, growth-related 25 kDa protein antibody, heat shock 25 kDa protein antibody, heat shock 27 kDa protein antibody, heat shock 27 kDa protein 1 antibody, heat shock 27kDa protein 1 transcript variant 1 antibody, heat shock 27kD protein 1 antibody, heat-shock protein antibody, heat shock protein 1 antibody, heat shock protein antibody, 25 kDa antibody, heat shock protein 27 antibody, heat shock protein antibody, alpha-crystallin-related antibody, 1 antibody, heat shock protein beta-1 antibody, heat shock protein HSP27-like protein antibody, HMN2B antibody, HS.76067 antibody, hsp1 antibody, Hsp25 antibody, HSP 25 antibody, Hsp27 antibody, HSP 27 antibody, Hsp27alpha antibody, hsp28 antibody, inhibitor of actin polymerization antibody, p25 antibody, SRP27 antibody, stress-responsive protein 27 antibody, truncated hsp25 antibody
Cross Reactivity Human
Applications ELISA, IP, WB
Immunogen Hsp27 antibody was raised in Mouse using a recombinant human protein purified from E.coli (His-HSP27) as the immunogen

Images

Western Blot analysis using Hsp27 antibody (10R-8577)

Specifications

Host Mouse
Clone AF5E5
Isotype IgG2b kappa
Method of Purification Hsp27 antibody was purified by ammonium sulfate precipitation
Form & Buffer Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol

Usage & Assay Information

Usage Recommendations WB: 1:1000, IP: 2 ul

Storage & Safety

Storage Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles

General Information

Biological Significance Hsp27 has a molecular weight of approximately 27 kDa, although it has been shown to form large aggregates of up to 800 kDa in the cytosol. Hsp27 is found in several types of human cells, including tumour cells. Hsp27 interferes with apoptosis through its ability to interact with and inhibit key components of the apoptotic signaling pathway, including the caspase activation complex. Overexpression of heat shock proteins can increase the tumorigenic potential of tumour cells. HSP27 also has been reported to be involved in development and progression of hormone-refractory prostate cancer.

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Images

  • Western Blot analysis using Hsp27 antibody (10R-8577) |

Availability: In stock

Price: $295.00
Size: 100 ul
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