HTR3A antibody (70R-10552)

Affinity purified rabbit polyclonal HTR3A antibody

Synonyms Polyclonal HTR3A antibody, Anti-HTR3A antibody, HTR3A, serotonin receptor 3A antibody, HTRA-3 antibody, HTRA 3, HTRA-3, HTRA 3 antibody, 5-hydroxytryptamine
Cross Reactivity Human, Mouse, Rat, Dog
Applications WB
Immunogen HTR3A antibody was raised in rabbit using the N terminal of HTR3A as the immunogen
Assay Information HTR3A Blocking Peptide, catalog no. 33R-5161, is also available for use as a blocking control in assays to test for specificity of this HTR3A antibody

Images

Immunohistochemical staining using HTR3A antibody (70R-10552)

HTR3A antibody was used for immunohistochemistry at a concentration of 4-8 ug/ml to stain Epithelial cells of renal tubule (lndicated with Arrows] and renal corpuscle (Indicated with Arrow Heads) in Human Kidney. Magnification is at 400X

Specifications

Host Rabbit
Form & Buffer Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 0.2-1 ug/ml

Storage & Safety

Storage Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles.

General Information

Biological Significance HTR3A belongs to the ligand-gated ion channel receptor superfamily. It is the subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified.

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Images

  • Immunohistochemical staining using HTR3A antibody (70R-10552) | HTR3A antibody was used for immunohistochemistry at a concentration of 4-8 ug/ml to stain Epithelial cells of renal tubule (lndicated with Arrows] and renal corpuscle (Indicated with Arrow Heads) in Human Kidney. Magnification is at 400X
  • Western Blot analysis using HTR3A antibody (70R-10552) | HTR3A antibody (70R-10552) used at 0.2-1 ug/ml to detect target protein.

Availability: In stock

Price: $345.00
Size: 50 ug
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