Human EGFR ELISA kit (55R-2055)

ELISA Kit for detection of EGFR in the research laboratory

Synonyms ERBB ELISA kit, ERBB1 ELISA kit, HER1 ELISA kit, PIG61 ELISA kit, MENA ELISA kit, Avian erythroblastic leukemia viral (v-erb-b) oncogene homolog ELISA kit, Cell growth inhibiting protein 40 ELISA kit, Cell proliferation-inducing protein 61 ELISA kit, Epidermal growth factor recept ELISA kit
Specificity Human EGFR
Applications ELISA
Assay Information Assay Time: 1-5 hours; Sample Volume: 50-100 ul; Detection Wavelength: 450 nm

Storage & Safety

Storage Store unopened kit at 2-8 deg C, do not use past expiration date

General Information

Biological Significance The epidermal growth factor receptor (EGFR) is a receptor tyrosine kinase of the ErbB family. Four members of the ErbB family have been identified; EGFR (ErbB1, HER1), ErbB2 (HER2), ErbB3 (HER3) and ErbB4 (HER4). EGFR signaling is initiated by ligand binding to the extracellular ligand binding domain. This initiates receptor homo-/hetero-dimerization and autophosphorylation by the intracellular kinase domain, resulting in receptor activation. Following activation, phosphorylation of cytoplasmic substrates occurs and a signaling cascade is initiated that drives many cellular responses, including changes in gene expression, cytoskeletal rearrangement, anti-apoptosis and increased cell proliferation.

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Availability: In stock

Price: $505.00
Size: 96 tests
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