Human IGF2R ELISA kit (55R-2193)

ELISA Kit for detection of IGF2R in the research laboratory

Synonyms CD222 ELISA kit, CIMPR ELISA kit, M6P-R ELISA kit, MPR1 ELISA kit, MPRI ELISA kit, Cation-independent mannose-6 phosphate receptor ELISA kit
Specificity Human IGF2R
Applications ELISA
Assay Information Detection Range: 312.5 pg/ml -20000 pg/ml; Sensitivity: 80 pg/ml; Assay Time: 1-5 hours; Sample Volume: 50-100 ul; Detection Wavelength: 450 nm

Storage & Safety

Storage Store unopened kit at 2-8 deg C, do not use past expiration date

General Information

Biological Significance IGF2R is a receptor for both, insulin-like growth factor 2 (IGF2) and mannose 6-phosphate (M6P). The IGF2 and M6P binding sites are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of IGF2. While the mouse Igf2r gene shows exclusive expression from the maternal allele, imprinting of the human IGF2R gene appears to be polymorphic, with only a minority of individuals showing expression from the maternal allele.

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Availability: In stock

Price: $545.00
Size: 96 tests
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