Human IgG3 protein (31-AI19)

Purified nativeHuman IgG3 protein

Synonyms Human IgG3 Whole Molecule, Immunoglobulin G3 Protein
Species Human
Applications User optimized

Images

SDS-PAGE analysis of Human IgG3 protein (31-AI19)

4-12% Bis-Tris NuPAGE gel showing the following lanes: 1- MW standard; 2- IgG3 (5 ug reduced/heated); 3- IgG3 (10 ug reduced/heated); 4- IgG3 (20 ug reduced/heated); 5- IgG3 (5 ug non-reduced/no heat); 6- IgG3 (10 ug non-reduced/no heat); 7- IgG3 (20 ug non-reduced/no heat)

Specifications

Source Human normal plasma
Purity > 95% pure
Molecular Weight 170 kDa
Form & Buffer 20mM phosphate, pH 7.4, with 150mM NaCl and 0.05% NaN3.
Concentration Batch dependent - please inquire should you have specific requirements

Storage & Safety

Storage Store at 4 deg C. DO NOT FREEZE.
Biohazard Information Donor samples were tested and found to be negative for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2. Nonetheless caution should be used when handling this material as there is a margin of error in all tests. This product contains sodium

General Information

Biological Significance Like IgG1, IgG3 activates complement and has an affinity for fc receptors; thus IgG1 and IgG3 are the more effective of the IgG subclasses. An IgG3 deficiency is associated with Wiscott-Aldrich disease, systemic lupus erythematosus, juvenile diabetes mellitus, and peridontal infections. IgG anti-viral antibodies are restricted to IgG subclasses 1 and 3, with IgG3 antibodies being the first to appear in response to infection.

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Images

  • SDS-PAGE analysis of Human IgG3 protein (31-AI19) | 4-12% Bis-Tris NuPAGE gel showing the following lanes: 1- MW standard; 2- IgG3 (5 ug reduced/heated); 3- IgG3 (10 ug reduced/heated); 4- IgG3 (20 ug reduced/heated); 5- IgG3 (5 ug non-reduced/no heat); 6- IgG3 (10 ug non-reduced/no heat); 7- IgG3 (20 ug non-reduced/no heat)

Availability: In stock

Price: $225.00
Size: 1 mg
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