Human IL1 alpha ELISA kit (55R-1602)

ELISA kit for the detection of IL1 alpha in the research laboratory

Synonyms Human Interleukin 1 alpha ELISA kit, IL1-alpha ELISA kit
Applications ELISA
Assay Information Sensitivity: 4.7 pg/ml-300 pg/ml

Images

ELISA assay using Human IL1 alpha ELISA kit (55R-1602)

Graph showing ELISA absorbance curve (O.D.) of Human IL1a (pg/ml)

Specifications

Form & Buffer This Kit contains: Lyophilized recombinant human IL-1 alpha standard: 10ng/tube

Storage & Safety

Storage Store at 4 deg C for short term storage (4 months) or -20 deg C for long term storage (8 months)

General Information

Biological Significance The interleukin1 (IL1) species represent an important family of biologically active mono nuclear cellderived proteins which are involved in inflammatory reactions and in immune responses. Two distinct human IL1 species, IL1 alpha and IL1 beta, have been identified. They share similarities such as the same molecular weight, similar biological effects and the same receptors on target cells. IL1 proteins are produced by macrophages, monocytes and various other cell types such as adult T cell leukemias, fibroblasts, epithelial or endothelial cells, neutrophils and astrocytes. Their biological properties include pyrogenicity, bone resorption, presentation of antigen to T cells and stimulation of B and T lymphocyte proliferation. IL1 alpha is an extracellular peptide of 17 kDa, its activity has been demonstrated in various biological fluids including serum, synovial fluid, gingival fluid, amniotic fluid, sputum, cerebrosinal fluid, urine, andbronchoalveolar lavage (BAL) fluid. Elevated serum or blood levels of IL1 alpha have been found in patients withtotal hip replacement/arthroplasties, in patients with recently diagnosted IDDM, in the instance of several carcinomas such as head and neck cancer, pancreatic cancer and thyroid cancer, in experimental acute pyelonephritis, in acute viral hepatitis and in septic shock. Both elevations in serum levels and joint fluids (synovial fluids) are detected in rheumatoid arthritis. IL1 alpha elevation is a marker for dental diseases such as pulpal inflammation and infections of the root canals.

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Images

  • <div><font face=Calibri size=2>ELISA assay using Human IL1 alpha ELISA kit (55R-1602)</font></div>     | Graph showing ELISA absorbance curve (O.D.) of Human IL1a (pg/ml)

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Price: $285.00
Size: 1 kit
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