ICAD antibody (10R-8583)

Mouse monoclonal ICAD antibody

Synonyms Monoclonal ICAD antibody, Anti-ICAD antibody, DFFA antibody, DNA fragmentation factor antibody, 45kDa antibody, alpha polypeptide antibody, BOS_15806 antibody, DFF1 antibody, DFF35 antibody, DFF45 antibody, DFF-45 antibody, DNA fragmentation factor 45 kDa subunit antibody, DNA fragmentation factor antibody, alpha polypeptide antibody, DNA fragmentation factor antibody, alpha subunit antibody, DNA fragmentation factor subunit alpha antibody, H13 antibody, ICAD antibody, ICAD-L antibody, ICAD-S antibody, inhibitor of CAD antibody, RP23-121D17.3 antibody
Cross Reactivity Human
Applications ELISA, IP
Immunogen ICAD antibody was raised in Mouse using a recombinant human protein purified from E.coli (His-ICAD) as the immunogen

Images

Western Blot analysis using ICAD antibody (10R-8583)

Specifications

Host Mouse
Clone AF41E3
Isotype IgG2a kappa
Method of Purification ICAD antibody was purified by ammonium sulfate precipitation
Form & Buffer Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol

Usage & Assay Information

Usage Recommendations IP: 2 ul

Storage & Safety

Storage Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles

General Information

Biological Significance Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. ICAD is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3.

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Images

  • Western Blot analysis using ICAD antibody (10R-8583) |

Availability: In stock

Price: $295.00
Size: 100 ul
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