ID2 protein (His tag) (80R-2695)
Purified recombinant ID2 protein (His tag)
|Synonyms||Inhibitor of DNA binding 2 protein, bHLHb26 protein, GIG8 protein, ID2A protein, ID2H protein, MGC26389 protein, ID2, ID 2, ID-2, ID 2 protein, ID-2 protein|
SDS-PAGE analysis of ID2 protein (His tag) (80R-2695)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-134 aa: MGSSHHHHHH SSGLVPRGSH MKAFSPVRSV RKNSLSDHSL GISRSKTPVD DPMSLLYNMN DCYSKLKELV PSIPQNKKVS KMEILQHVID YILDLQIALD SHPTIVSLHH QRPGQNQASR TPLTTLNTDI SILSLQASEF PSELMSNDSK ALCG|
|Purity||> 85% pure|
|Molecular Weight||17.0 kDa|
|Form & Buffer||Supplied in liquid form in 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.4M Urea|
Storage & Safety
|Storage||Can be stored at 4 deg C for short terms (1-2 weeks). For long term storage, aliquot and store at -20 deg C or -70 deg C. Avoid repeated freezing and thawing cycles|
|Biological Significance||ID2 belongs to the inhibitor of DNA binding (ID) family, members of which are transcriptional regulators that contain a helix-loop-helix (HLH) domain but not a basic domain. Members of the ID family inhibit the functions of basic helix-loop-helix transcription factors in a dominant-negative manner by suppressing their heterodimerization partners through the HLH domains. This protein may play a role in negatively regulating cell differentiation. Recombinant human ID2 protein, fused to His-tag at N-terminus, was expressed in E.coli.|
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