IFN alpha2b protein (30R-1077)
Purified recombinant Human IFN alpha2b protein
|Synonyms||IFN alphab -2, Interferon a-2b protein, IRF-2-binding protein 1 protein, IFN alphab -2 protein, IFN alphab 2 protein, IRF2BP1 protein, interferon regulatory factor 2 binding protein 1 protein, IRF-2BP1 protein, IRF-2BP1, IFN alphab 2, DKFZP434M154 protein, IFN alpha2b, Interferon regulatory factor 2-binding protein 1 protein|
Coomassie Blue stained SDS-PAGE of IFN alpha2b protein (30R-1077)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||24-188 amino acids: MCDLPQTHSL GSRRTLMLLA QMRRISLFSC LKDRHDFGFP QEEFGNQFQK AETIPVLHEM IQQIFNLFST KDSSAAWDET LLDKFYTELY QQLNDLEACV IQGVGVTETP LMKEDSILAV RKYFQRITLY LKEKKYSPCA WEVVRAEIMR SFSLSTNLQE SLRSKE|
|Purity||> 95% pure|
|Molecular Weight||19.4 kDa (166aa), confirmed by MALDI-TOF.|
|Form & Buffer||Supplied as a liquid in PBS, pH 7.4.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||Interferon induces a variety of effects on target cells including antiviral, antiproliferative, and immunomodulatory activities. Interferon alpha-2b can either inhibit or enhance immune cell activity within the tightly regulated microenvironment of inflammation, depending upon the concentration of the cytokine and the activation stage of the cell. Interferon alpha-2b was expressed in E. coli and purifed by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.|
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