IGF1R antibody (10R-2108)

Mouse monoclonal IGF1R antibody

Synonyms Monoclonal IGF1R antibody, Anti-IGF1R antibody, Insulin-like growth factor 1 receptor antibody, IGFR 1 antibody, IGF1R, JTK13 antibody, CD221 antibody, CD221 antigen antibody, IGF-I receptor antibody, IGFR-1 antibody, IGFR 1, IGF I receptor antibody, IGFR-1
Cross Reactivity Human
Applications ELISA, IHC, WB
Immunogen IGF1R antibody was raised in Mouse using a purified recombinant fragment of IGF1R expressed in E. coli as the immunogen.

Images

Immunohistochemical staining using IGF1R antibody (10R-2108)

Immunohistochemical analysis of paraffin-embedded human gastric adenocarcinoma(A), colon adenocarcinoma(B), endometrial carcinoma(uterus)(C), ovary adenocarcinoma(D), lung squamous cell carcinoma(E), stomach epithelium mucosae(F), showing membrane localization using IGF1R antibody with DAB staining.

Specifications

Host Mouse
Clone 3C8B1
Isotype IgG2b
Form & Buffer Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.
Concentration 1.0 mg/ml

Usage & Assay Information

Usage Recommendations ELISA: 1:10,000, IHC: 1:200-1:1000, WB: 1:500-1:2000

Storage & Safety

Storage Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance IGF1R binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-likegrowth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha andbeta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent byenhancing cell survival.

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Images

  • Immunohistochemical staining using IGF1R antibody (10R-2108) | Immunohistochemical analysis of paraffin-embedded human gastric adenocarcinoma(A), colon adenocarcinoma(B), endometrial carcinoma(uterus)(C), ovary adenocarcinoma(D), lung squamous cell carcinoma(E), stomach epithelium mucosae(F), showing membrane localization using IGF1R antibody with DAB staining.
  • Western Blot analysis using IGF1R antibody (10R-2108) | Western Blot showing IGF1R antibody used against truncated IGF1R recombinant protein.

Availability: In stock

Price: $345.00
Size: 100 ul
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