IGF1R antibody (10R-2111)

Mouse monoclonal IGF1R antibody

Synonyms Monoclonal IGF1R antibody, Anti-IGF1R antibody, Insulin-like growth factor 1 receptor antibody, CD221 antibody, CD221 antigen antibody, IGFR 1 antibody, IGFR 1, IGF I receptor antibody, IGFR-1, IGF-I receptor antibody, IGFR-1 antibody, JTK13 antibody, IGF1R
Cross Reactivity Human
Applications ELISA, IHC, WB
Immunogen IGF1R antibody was raised in Mouse using a purified recombinant fragment of IGF1R expressed in E. coli as the immunogen.

Images

Immunohistochemical staining using IGF1R antibody (10R-2111)

Immunohistochemical analysis of paraffin-embedded rectum cancer tissues using IGF1R antibody with DAB staining.

Specifications

Host Mouse
Clone 3G5C1
Isotype IgG2a
Form & Buffer Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.
Concentration 1.0 mg/ml

Usage & Assay Information

Usage Recommendations ELISA: 1:10,000, IHC: 1:200-1:1000, WB: 1:500-1:2000

Storage & Safety

Storage Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance IGF1R binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-likegrowth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha andbeta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent byenhancing cell survival.

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Images

  • Immunohistochemical staining using IGF1R antibody (10R-2111) | Immunohistochemical analysis of paraffin-embedded rectum cancer tissues using IGF1R antibody with DAB staining.
  • Western Blot analysis using IGF1R antibody (10R-2111) | Western Blot showing IGF1R antibody used against truncated IGF1R recombinant protein.
  • Immunohistochemical staining using IGF1R antibody (10R-2111) | Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues using IGF1R antibody with DAB staining.

Availability: In stock

Price: $345.00
Size: 100 ul
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