IGF1R antibody (70R-10422)

Affinity purified rabbit polyclonal IGF1R antibody

Synonyms Polyclonal IGF1R antibody, Anti-IGF1R antibody, IGFIR antibody, MGC142170 antibody, JTK13 antibody, IGFR 1 antibody, IGF1R, IGFR 1, MGC18216 antibody, MGC142172 antibody, IGFR-1 antibody, CD221 antibody, insulin-like growth factor 1 receptor antibody, IGFR-1
Cross Reactivity Human, Mouse, Rat, Pig, Bovine, Chicken, Zebrafish, African Clawed Frog
Applications IHC, WB
Immunogen IGF1R antibody was raised in rabbit using the middle region of IGF1R as the immunogen
Assay Information IGF1R Blocking Peptide, catalog no. 33R-2144, is also available for use as a blocking control in assays to test for specificity of this IGF1R antibody

Images

Immunofluorescent staining using IGF1R antibody (70R-10422)

IGF1R antibody used at a concentration of 2-10 ug/ml to detect mouse skeletal muscle (red). Nuclei staining with DAPI. Not suitable for human.

Specifications

Host Rabbit
Form & Buffer Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 0.2-1 ug/ml

Storage & Safety

Storage Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles.

General Information

Biological Significance This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival.

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Images

  • Immunofluorescent staining using IGF1R antibody (70R-10422) | IGF1R antibody used at a concentration of 2-10 ug/ml to detect mouse skeletal muscle (red). Nuclei staining with DAPI. Not suitable for human.
  • Western Blot analysis using IGF1R antibody (70R-10422) | IGF1R antibody (70R-10422) used at 0.2-1 ug/ml to detect target protein.

Availability: In stock

Price: $345.00
Size: 50 ug
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