IGF1R antibody (70R-14283)

Affinity purified Rabbit polyclonal IGF1R antibody

Synonyms Polyclonal IGF1R antibody, Anti-IGF1R antibody, CD221 antibody, JTK13 antibody, IGF1R, insulin-like growth factor 1 receptor antibody, IGFR 1, IGFR-1, IGFR-1 antibody, MGC142172 antibody, IGFR 1 antibody, IGFIR antibody, MGC142170 antibody, MGC18216 antibody
Applications IHC-P, WB
Immunogen IGF1R antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence at the C-terminal of human IGF1R, different from the related rat and Rabbit sequences by one amino acid, as the immunogen

Images

Immunohistochemical staining using IGF1R antibody (70R-14283)

Immunohistochemistry of paraffin-embedded section of Rat Pancreatic Gland Tissue

Specifications

Host Rabbit
Isotype IgG
Method of Purification IGF1R antibody was purified by affinity chromatography
Form & Buffer Supplied in lyophilized form

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by the end user

Storage & Safety

Storage Store at 4 deg C for short term storage. For long term storage aliquot and store at -20 deg C, avoid repeated freeze/thaw cycles.

General Information

Biological Significance This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival.

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Images

  • <div><font face=Calibri size=2>Immunohistochemical staining using IGF1R antibody (70R-14283)</font></div>     | Immunohistochemistry of paraffin-embedded section of Rat Pancreatic Gland Tissue
  • <div><font face=Calibri size=2>Western Blot analysis using IGF1R antibody (70R-14283)</font></div>     | Lane 1: 293T Cell Lysate; Lane 2: A549 Cell Lysate; Lane 3: MCF-7 Cell Lysate

Availability: In stock

Price: $255.00
Size: 100 ug
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