IGF2 antibody (70-IR16)

Affinity purified Rabbit polyclonal IGF2 antibody

Synonyms Polyclonal IGF2 antibody, Anti-IGF2 antibody, IGF 2, IGF 2 antibody, IGF2, IGF-2 antibody, IGF-2 antibody, Insulin-like Growth Factor-2 antibody, IGF-2, Somatamedin A antibody
Specificity Human IGF2
Cross Reactivity To be determined by end-user
Applications ELISA, Inhibition, WB
Immunogen IGF2 antibody was raised in rabbit using highly pure recombinant human IGF-II (human IGF-II) as the immunogen.

Specifications

Host Rabbit
Form & Buffer Lyophilized from PBS, pH 7.2. Reconstitute in sterile water at a concentration of 0.1-1.0 mg/ml.

Usage & Assay Information

Usage Recommendations ELISA: 0.5-2 ug/ml, Inhibition: 3.1-4.6 ug/ml, WB: 0.1-0.2 ug/ml

Storage & Safety

Storage Store at -20 deg C until reconstitution. Following reconstitution product may be stored at 4 deg C in the short term. For long term storage aliquot and freeze at -20 deg C. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance The IGFs are mitogenic polypeptide growth factors that stimulate the proliferation and survival of various cell types including muscle, bone, and cartilage tissue in vitro. IGFs are predominantly produced by the liver, although a variety of tissues produce the IGFs at distinctive times. The IGFs belong to the Insulin gene family, which also contains insulin and relaxin. The IGFs are similar by structure and function to insulin, but have a much higher growth-promoting activity than insulin. IGF-II expression is influenced by placenta lactogen, while IGF-I expression is regulated by growth hormone. Both IGF-I and IGF-II signal through the tyrosine kinase type I receptor (IGF-IR), but, IGF-II can also signal through the IGF-II/Mannose-6-phosphate receptor.

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Availability: In stock

Price: $275.00
Size: 50 ug
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