IGF2 protein (30R-1836)
Purified recombinant Human IGF2 protein
|Synonyms||Somatomedin-A protein, IGF2, IGF 2, IGF-2 protein, IGF 2 protein, INSIGF, IGF-2, Insulin-like growth factor 2 protein|
Coomassie Blue stained SDS-PAGE of IGF2 protein (30R-1836)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||25-91 amino acids: MAYRPSETLC GGELVDTLQF VCGDRGFYFS RPASRVSRRS RGIVEECCFR SCDLALLETY CATPAKSE|
|Purity||> 90% pure|
|Molecular Weight||7.6 kDa (68aa), confirmed by MALDI-TOF|
|Form & Buffer||Supplied as a liquid in PBS, pH 7.4, containing 10% glycerol.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||IGF2, as known as insulin-like growth factor 2, is a mitogenic polypeptide growth factor that stimulates the proliferation and survival of various cell types including muscle, bone, and cartilage tissue in vitro. This protein is a fetal growth factor, influenced by placental lactogen and abundantly expressed by placental trophoblasts. Recombinant human IGF2 was expressed in E. coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.|
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