IGFBP7 protein (His tag) (80R-3616)
Purified recombinant IGFBP7 protein (His tag)
|Synonyms||AGM protein, FSTL2 protein, IBP-7 protein, IGFBP-7 protein, IGFBP-7v protein, IGFBPRP1 protein, MAC25 protein, PSF protein, RAMSVPS protein, TAF protein, IGFBP 7 protein, IGFBP-7 protein|
Coomassie blue stained SDS-PAGE of IGFBP7 protein (His tag) (80R-3616)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||27-282 aa: MGSSHHHHHH SSGLVPRGSH MGSSSSDTCG PCEPASCPPL PPLGCLLGET RDACGCCPMC ARGEGEPCGG GGAGRGYCAP GMECVKSRKR RKGKAGAAAG GPGVSGVCVC KSRYPVCGSD GTTYPSGCQL RAASQRAESR GEKAITQVSK GTCEQGPSIV TPPKDIWNVT GAQVYLSCEV IGIPTPVLIW NKVKRGHYGV QRTELLPGDR DNLAIQTRGG PEKHEVTGWV LVSPLSKEDA GEYECHASNS QGQASASAKI TVVDALHEIP VKKGEGAEL|
|Purity||> 85% pure|
|Method of Purification||IGFBP7 protein was purified by using conventional chromatography techniques|
|Molecular Weight||28.8 kDa|
|Form & Buffer||Supplied in liquid form in 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 50% glycerol, 2mM DTT, 1mM EDTA|
Storage & Safety
|Storage||Can be stored at 4 deg C short term (1-2 weeks). For long term storage, aliquot and store at -20 deg C or -70 deg C. Avoid repeated freezing and thawing cycles.|
|Biological Significance||IGFBP7 is a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm Recombinant human IGFBP7 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.|
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