IL1 beta antibody (biotin) (60R-IR023bt)

Rabbit polyclonal IL1 beta antibody (biotin) conjugated

Synonyms Polyclonal IL1 beta antibody, Anti-IL1 beta antibody, Endogenous Pyrogen antibody, LEM antibody, Mononuclear Cell Factor antibody, Interleukin 1 beta antibody, IL beta 1, Leukocyte Endogenous Mediator antibody, IL1 beta, EP antibody, IL beta 1 antibody, Catabolin antibody, MCF antibody, Lymphocyte-activating factor antibody, LAF antibody, IL-1 beta antibody, IL beta-1, IL beta-1 antibody
Specificity Murine IL-1 beta
Cross Reactivity To be determined by end-user
Applications ELISA, WB
Immunogen IL1 beta antibody (biotin) was raised in rabbit using highly pure recombinant murine IL-1-beta as the immunogen.

Specifications

Host Rabbit
Molecular Weight 17.3 kDa (predicted detection band MW)
Tag/Conjugate Biotin
Form & Buffer Lyophilized from PBS, pH 7.2.

Usage & Assay Information

Usage Recommendations ELISA: 0.25-1 ug/ml, WB: 0.1-0.2 ug/ml

Storage & Safety

Storage Store at -20 deg C until reconstitution. Following reconstitution product may be stored at 4 deg C in the short term. For long term storage aliquot and freeze at -20 deg C. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance IL1beta is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL1a and IL1beta binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL2 release, B-cell maturation and proliferation, mitogenic FGFlike activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL1beta is a secreted cytokine, IL1a is predominantly a cell-associated cytokine.

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Availability: In stock

Price: $225.00
Size: 25 ug
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