IL1 beta protein (30R-1119)

Purified recombinant Human IL1 beta protein

Synonyms IL beta 1 protein, IL1-beta protein, IL1B protein, Interleukin 1b protein, IL beta 1, IL-1B, Interleukin 1beta protein, IL1F2 protein, beta proprotein protein, IL-1 protein, IL beta-1, IL1 beta, interleukin 1 beta protein, Interleukin 1 protein, IL beta-1 protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

Coomassie Blue stained SDS-PAGE of IL1 beta protein (30R-1119)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 117-269 amino acids: MAPVRSLNCT LRDSQQKSLV MSGPYELKAL HLQGQDMEQQ VVFSMSFVQG EESNDKIPVA LGLKEKNLYL SCVLKDDKPT LQLESVDPKN YPKKKMEKRF VFNKIEINNK LEFESAQFPN WYISTSQAEN MPVFLGGTKG GQDITDFTMQ FVSS
Expression System E.coli
Purity > 95% pure
Molecular Weight 17 kDa (154aa), confirmed by MALDI-TOF.
Form & Buffer Supplied as a liquid in PBS, pH 7.4.
Concentration 1 mg/ml

Storage & Safety

Storage Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Endotoxin Levels < 1.0 EU per ug of protein (determined by LAL method)

General Information

Biological Significance Interleukin-1 (IL-1) has been considered a potentially important inflammatory mediator. It is composed of two distinct proteins, called as IL-1 alpha and IL-1 beta. IL-1 beta is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1 alpha and IL-1 beta bind to the same receptor and they are structurally related polypeptides that share approximately 20% amino acid. Recombinant human IL-1 beta was expressed in E. coli and purified by using conventional chromatography techniques.

References
Add a Paper

Phapanin Charoenphol, Ryan B. Huang, Omolola Eniola-Adefeso

Potential role of size and hemodynamics in the efficacy of vascular-targeted spherical drug carriers

Biomaterials

Volume: 31 Issue: 6 Page: 1392-1402 DOI: 10.1016/j.biomaterials.2009.11.007

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Images

  • Coomassie Blue stained SDS-PAGE of IL1 beta protein (30R-1119) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: $255.00
Size: 100 ug
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