IL10 protein (Mouse) (30R-AI005)

Purified recombinant Mouse IL10 protein

Synonyms B-TCGF protein, CSIF protein, IL-10 protein, IL 10 protein, TGIF protein, IL 10, IL-10, IL-10 protein, Interleukin 10 protein, IL10
Species Mouse
Protein Type Recombinant
Applications User optimized

Specifications

Residues Region of IL10 protein corresponding to amino acids MSRGQYSRED NNCTHFPVGQ SHMLLELRTA FSQVKTFFQT KDQLDNILLT DSLMQDFKGY LGCQALSEMI QFYLVEVMPQ AEKHGPEIKE HLNSLGQKLK TLRMRLRRCH RFLPCENKSK AVEQVKSDFN KLEDQGVYKA MNEFDIFINC IEAYMMIKMK S.
Expression System E.coli
Purity > 98% pure
Molecular Weight 18.7 kDa
Form & Buffer Lyophilized from 10mM Sodium Phosphate, pH 7.0, sterile filtered through a 0.2 um filter. Reconstitute in water to a concentration of 0.1-1.0mg/ml.

Usage & Assay Information

Bioactivity PeproTech's Mouse IL-10 is fully biologically active as measured by the dose-dependent co-stimulation (with IL-4) of the proliferation of Mouse MC/9 cells. The ED50 was found to be 5 x 10^5 units/mg.

Storage & Safety

Storage Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Endotoxin Levels Endotoxin level is less than 0.1 ng per ug (1 EU/ug).

General Information

Biological Significance IL10 is an immunosuppressive cytokine produced by a variety of mammalian cell types including macrophages, monocytes, T cells, B cells and keratinocytes. IL10 inhibits the expression of proinflammatory cytokines such as IL1 and TNFa. Like IL4, IL10 enhances humoral immune responses and attenuates cell-mediated immune reactions. Human IL10 active on Mouse cells, but Mouse IL10 is inactive on human cells.

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Availability: In stock

Price: $225.00
Size: 10 ug
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