IL1RN protein (His tag) (80R-2256)
Purified recombinant Mouse IL1RN Protein (His tag)
|Synonyms||IL1RN, IL-1ra protein, ILRN 1 protein, ILRN 1, Interleukin 1 receptor antagonist protein, ILRN-1 protein, ILRN-1, F630041P17Rik protein|
Coomassie Blue stained SDS-PAGE of IL1RN protein (His tag) (80R-2256)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||MGSSHHHHHH SSGLVPRGSH MGSHMRPSGK RPCKMQAFRI WDTNQKTFYL RNNQLIAGYL QGPNIKLEEK IDMVPIDLHS VFLGIHGGKL CLSCAKSGDD IKLQLEEVNI TDLSKNKEED KRFTFIRSEK GPTTSFESAA CPGWFLCTTL EADRPVSLTN TPEEPLIVTK FYFQEDQ|
|Purity||> 95% pure|
|Molecular Weight||20.0 kDa|
|Form & Buffer||Supplied in liquid form in 20mM Tris-HCl buffer, pH 8.0 containing 0.1M NaCl, 10% glycerol.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||IL1RN is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer.|
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