IL20 protein (30R-AI115)

Purified recombinant Human IL20 protein

Synonyms Interleukin 20 protein, IL-20 protein, IL-20, IL 20 protein, IL 20, IL20, IL-20 protein
Species Human
Protein Type Recombinant
Applications User optimized

Specifications

Residues Region of IL20 protein corresponding to amino acids MLKTLNLGSC VIATNLQEIR NGFSEIRGSV QAKDGNIDIR ILRRTESLQD TKPANRCCLL RHLLRLYLDR VFKNYQTPDH YTLRKISSLA NSFLTIKKDL RLCHAHMTCH CGEEAMKKYS QILSHFEKLE PQAAVVKALG ELDILLQWME ETE.
Expression System E.coli
Purity > 98% pure
Molecular Weight 35.2 kDa
Form & Buffer Supplied as lyophilized powder.

Usage & Assay Information

Bioactivity Determined by its ability to activate STAT following receptor ligand interaction.

Storage & Safety

Storage Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Endotoxin Levels Endotoxin level is less than 0.1 ng per ug (1 EU/ug).

General Information

Biological Significance IL20 is a member of the IL10 family of regulatory cytokines which includes IL10, IL19, IL20, IL22, IL24 and IL26. Members of this family share partial homology in their amino acid sequences but they are dissimilar in their biological functions. IL20 is a hematopoietic growth factor capable of stimulating colony formation by CD34+ multipotential progenitors, but not by other progenitor cells. IL20 signals through a receptor system composed of type I IL20R-a and type II IL20R-beta. Over-expression of IL20 in keratinocytes expressing both receptor subunits has been implicated in the induction of inflammatory skin disease.

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Availability: In stock

Price: $225.00
Size: 10 ug
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