IL4 antibody (10-I74A)

Mouse monoclonal IL4 antibody

Synonyms Monoclonal IL4 antibody, Anti-IL4 antibody, Interleukin 4 antibody, B cell stimulating factor antibody, IL4, BSF-1 antibody, IL-4 antibody, IL-4 antibody, IL 4, BCGF antibody, BCDF antibody, IL-4, IL 4 antibody
Specificity Human IL-4
Cross Reactivity To be determined by end-user
Applications ELISA, Inhibition, WB
Immunogen IL4 antibody was raised in mouse using recombinant human IL-4 as the immunogen.

Specifications

Host Mouse
Clone M6110641
Isotype IgG2a
Molecular Weight 14.0 kDa (predicted detection band MW)
Form & Buffer Purified murine ascites, supplied in PBS buffer, pH 7.2 with no preservatives added.

Usage & Assay Information

Usage Recommendations ELISA: 0.5-1 ug/ml, Inhibition: 6.0-8.5 ug/ml, ib: 0.2-0.5 ug/ml

Storage & Safety

Storage Store at -20 deg C until reconstitution. Following reconstitution product may be stored at 4 deg C in the short term. For long term storage aliquot and freeze at -20 deg C. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance IL4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. Produced by mast cells, T cells and bone marrow stromal cells, IL4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL4, IL5, IL6, IL10, and IL13, which favor a humoral immune response. Another dominant function of IL4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL4 production by Th2 cells has been associated with elevated IgE production and allergy.

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Availability: In stock

Price: $240.00
Size: 250 ug
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