IL4 protein (His tag) (80R-3427)

Purified recombinant IL4 protein (His tag)

Synonyms IL-4 protein, IL 4 protein, B cell stimulatory factor 1 protein, BSF 1 protein, Binetrakin protein, Lymphocyte stimulatory factor 1 protein, Pitrakinra protein, Interleukin 4 protein
Species Human
Protein Type Recombinant
Applications ELISA, SDS-PAGE, WB

Images

Western blot analysis using IL4 protein (His tag) (80R-3427)

Specifications

Residues HKCDITLQEIIKTLNSLTEQKTLCTELTVTDIFAASKNTTEKETFCRAATVLRQFYSHHEKDTRCLGATA QQFHRHKQLIRFLKRLDRNLWGLAGLNSCPVKEANQSTLENFLERLKTIMREKYSKCSS
Expression System E.coli
Source His-fusion expressed in cell supernatent (soluble under denaturing conditions)
Purity > 90% pure
Molecular Weight 20 kDa
Tag/Conjugate His tag
Form & Buffer Supplied in liquid form in PBS buffer

Storage & Safety

Storage Store at 4 deg C in a working aliquot for 1 week. For long term storage, aliquot and freeze at -20 to -80 deg C, avoid repeat freeze/thaw cycles

General Information

Biological Significance IL4 participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Genetic variations in IL4 may be a cause of susceptibility to ischemic stroke (ISCHSTR); also known as cerebrovascular accident or cerebral infarction. A stroke is an acute neurologic event leading to death of neural tissue of the brain and resulting in loss of motor, sensory and/or cognitive function. Ischemic strokes, resulting from vascular occlusion, is considered to be a highly complex disease consisting of a group of heterogeneous disorders with multiple genetic and environmental risk factors.

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Images

  • Western blot analysis using IL4 protein (His tag) (80R-3427)

Availability: In stock

Price: $210.00
Size: 50 ug
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