IL6 antibody (10R-1787)
Mouse monoclonal IL6 antibody
|Synonyms||Monoclonal IL6 antibody, Anti-IL6 antibody, MGI-2 antibody, IL6, IL-6 antibody, IL-6, Interleukin 6 antibody, IL 6 antibody, BSF-2 antibody, HSF antibody, 26 kDa antibody antibody, IL-6 antibody, B cell differentiation factor antibody, IFN-beta2 antibody, BCDF antibody, HPGF antibody, IL 6|
|Immunogen||IL6 antibody was raised in Mouse using a purified recombinant fragment of human IL-6 expressed in E. coli as the immunogen.|
Western Blot analysis using IL6 antibody (10R-1787)
Western Blot showing IL6 antibody used against IL6 recombinant protein.
|Form & Buffer||Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.|
Usage & Assay Information
|Usage Recommendations||ELISA: 1:10,000, WB: 1:500-1:2000|
Storage & Safety
|Storage||Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||IL6 is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, IL6 has diverse biological functions. It stimulates B-cell differentiation and antibody production, synergizes with IL3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. IL6 signals through the IL6 receptor system that consists of two chains, IL6R alpha and gp130. Mouse IL6 is inactive on human cells, while both human and Mouse are equally active on Mouse cells.|
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