IL6 protein (30R-3027)

Purified recombinant IL6 protein

Synonyms B cell stimulatory factor 2 protein, BSF 2 protein, BSF2 protein, CDF protein, CTL differentiation factor protein, Cytotoxic T cell differentiation factor protein, Hepatocyte stimulating factor protein, HGF protein, HPGF protein, HSF protein, Hybridoma growth factor protein, Hybridoma plasmacytoma growth factor protein, IFNB2 protein, IL 6 protein, IL6 protein protein, Interferon beta 2 protein, Interleukin 6 protein, Interleukin6 protein
Species Human
Protein Type Recombinant
Applications WB

Images

Western Blot analysis using IL6 protein (30R-3027)

Specifications

Expression System E.coli
Purity > 95% pure
Molecular Weight 21 kDa
Form & Buffer Supplied in liquid form in PBS, 10% glycerol
Concentration 1mg/ml

Usage & Assay Information

Bioactivity The ED50 of IL-6 is typically 0.3-1 ng/ml. Measured in a cell proliferation assay using a murine myeloblastic cell line, B9.

Storage & Safety

Storage Store at -80 deg C. Avoid frequent freeze/thaw cycles

General Information

Biological Significance Interleukin-6 (IL-6) is a pleiotropic alpha-helical cytokine that plays important roles in a central player in the regulation of inflammation, haematopoiesis, immune response and host defense mechanisms. Human IL-6 molecular weight ranges between 21 and 28 kDa, depending on the state of glycosylation and phosphorylation. Mature human IL-6 is 183 amino acids and shares the homology between human and rat IL-6 is 41% at the amino acid level. IL-6 interacts with its receptor complex consisting of the membrane-bound IL-6 receptor (IL-6R) and the signal transducing protein gp130. IL-6R can exist as a soluble protein (sIL-6R), which binds the ligand IL-6.

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Images

  • Western Blot analysis using IL6 protein (30R-3027) |

Availability: In stock

Price: $245.00
Size: 20 ug
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