IL6 protein (His tag) (80R-1170)

Purified recombinant Human IL6 protein

Synonyms IL6 protein, HSF protein, beta 2) protein, IL-6 protein, IL-6, BSF2 protein, , IFNB2 protein, IL6, IL 6 protein, interleukin 6 (interferon protein, IL 6, IL-6 protein, HGF protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

Coomassie Blue stained SDS-PAGE of IL6 protein (His tag) (80R-1170)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 30-212 amino acids: MGSSHHHHHH SSGLVPRGSH MVPPGEDSKD VAAPHRQPLT SSERIDKQIR YILDGISALR KETCNKSNMC ESSKEALAEN NLNLPKMAEK DGCFQSGFNE ETCLVKIITG LLEFEVYLEY LQNRFESSEE QARAVQMSTK VLIQFLQKKA KNLDAITTPD PTTNASLLTK LQAQNQWLQD MTTHLILRSF KEFLQSSLRA LRQM
Expression System E.coli
Purity > 95% pure
Molecular Weight 23.1 kDa (204 aa), confirmed by MALDI-TOF.
Tag/Conjugate His tag
Form & Buffer Supplied as a liquid in PBS, pH 7.4, containing 10% glycerol.
Concentration 0.5 mg/ml

Storage & Safety

Storage Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Endotoxin Levels < 1.0 EU per ug of protein (determined by LAL method)

General Information

Biological Significance Interleukin-6, also known as IL-6, is an immunoregulatory lymphokine produced by T-cells in response to proteinic or mitogenic stimulation. It is also a 'myokine,' a cytokine produced from muscle, and is elevated in response to muscle contraction. IL-6 acts as both a pro-inflammatory and anti-inflammatory cytokine. Smooth muscle cells in the tunica media of many blood vessels also produce IL-6. It is mediated through its inhibitory effects on TNF-alpha and IL-1, and activation of IL-1ra and IL-10. Recombinant interleukin-6 was expressed in E. coli and purifed by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.

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Images

  • Coomassie Blue stained SDS-PAGE of IL6 protein (His tag) (80R-1170) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: $340.00
Size: 100 ug
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