ILK antibody (20R-2979)

Rabbit polyclonal ILK antibody

Synonyms Polyclonal ILK antibody, Anti-ILK antibody, ILK antibody, integrin-linked kinase antibody, 59 kDa serine/threonine-protein kinase antibody, beta-integrin-linked kinase antibody, BOS_14637 antibody, CG10504-PA antibody, CG10504-PB antibody, CT29478 antibody, Dmel_CG10504 antibody, DmILK antibody, EGK_06531 antibody, ESTM24 antibody, ILK-1 antibody, ILK-2 antibody, Ilk-PA antibody, Ilk-PB antibody, integrin binding protein kinase antibody, integrin linked kinase antibody, integrin-linked kinase-2 antibody, integrin-linked protein kinase antibody, integrin-linked protein kinase-like protein antibody, lost-contact antibody, main squeeze antibody, msq antibody, p59 antibody, p59ILK antibody, PANDA_014448 antibody, zilk antibody
Cross Reactivity Human, Mouse, Rat
Applications WB
Immunogen ILK antibody was raised in Rabbit using a recombinant human protein purified from E.coli as the immunogen

Images

Western Blot analysis using ILK antibody (20R-2979)

Specifications

Host Rabbit
Isotype IgG
Method of Purification ILK antibody was purified by affinity chromatography
Form & Buffer Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol

Usage & Assay Information

Usage Recommendations WB: 1:1000

Storage & Safety

Storage Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles

General Information

Biological Significance Integrin-linked kinase (ILK) is an adaptor and signaling protein that couples integrins to the actin cytoskeleton and coordinates signal transduction from extracellular matrix and growth factors. By interacting with the focal adhesion proteins PINCH, paxillin, and parvin, ILK regulates integrin-mediated cell adhesion and cytoskeletal dynamics within focal adhesions to regulate cell adhesion, spreading, and migration. ILK is involved in the suppression of apoptosis and promotion of cell survival through the phosphorylation of AKT (Ser473), GSK-3 (Ser9), myosin light chain (Ser18/19), and affixin. ILK activity is stimulated by PI3 kinase and negatively regulated by the tumor suppressor PTEN.

References
Add a Paper

Sorry, but there are no references currently for this product.

Reviews

You need to be logged in to write a review. Please login here

Sorry there are currently no reviews for this product

Images

  • Western Blot analysis using ILK antibody (20R-2979) |

Availability: In stock

Price: $295.00
Size: 100 ul
OR
Shipping
View Our Distributors