Inhibin alpha antibody (10R-1953)

Mouse monoclonal Inhibin alpha antibody

Synonyms Monoclonal Inhibin Alpha antibody, Anti-Inhibin Alpha antibody, INHA antibody, Inhibin Alpha antibody, INHA antibody, Anti Inhibin Alpha antibody
Cross Reactivity Human
Applications ELISA, IF, IHC
Immunogen Inhibin alpha antibody was raised in Mouse using a purified recombinant fragment of human INHA expressed in E. coli as the immunogen.

Images

Immunofluorescent staining using (Inhibin alpha antibody)

Confocal immunofluorescence analysis of Hela cells using INHA antibody (green). Red: Actin filaments have been labeled with DY-554 phalloidin. Blue: DRAQ5 fluorescent DNA dye.

Specifications

Host Mouse
Clone 4A2
Isotype IgG1
Form & Buffer Purified antibody supplied in PBS containing 0.03% sodium azide.
Concentration 1.0 mg/ml

Usage & Assay Information

Usage Recommendations ELISA: 1:10,000, IF: 1:200-1:1000, IHC: 1:200-1:1000

Storage & Safety

Storage Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance INHA joins either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. However, in prostate cancer, expression of the inhibin alpha-subunit gene was suppressed and was not detectable in poorly differentiated tumor cells. Furthermore, because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone.

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Images

  • Immunofluorescent staining using  (Inhibin alpha antibody) | Confocal immunofluorescence analysis of Hela cells using INHA antibody (green). Red: Actin filaments have been labeled with DY-554 phalloidin. Blue: DRAQ5 fluorescent DNA dye.
  • Immunohistochemical staining using Inhibin alpha antibody (10R-1953) | Immunohistochemical analysis of paraffin-embedded human lymphoid (A), ovary tumor (B) and testicle tumor (C) tissues using INHA antibody with DAB staining.

Availability: In stock

Price: $295.00
Size: 100 ul
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