INPPL1 antibody (70R-14287)

Affinity purified Rabbit polyclonal INPPL1 antibody

Synonyms Polyclonal INPPL1 antibody, Anti-INPPL1 antibody, INPPL 1 antibody, INPPL-1, INPPL-1 antibody, SHIP2 antibody, Inositol polyphosphate 5 phosphatase like 1 antibody, Inositol polyphosphate phosphatase like 1 antibody, INPPL 1, INPPL1
Applications IHC-P, WB
Immunogen INPPL1 antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence in the middle region of human INPPL1, identical to the related rat and Rabbit sequences, as the immunogen

Images

Immunohistochemical staining using INPPL1 antibody (70R-14287)

Immunohistochemistry of paraffin-embedded section of Human Intestinal, Cancer Tissue

Specifications

Host Rabbit
Isotype IgG
Method of Purification INPPL1 antibody was purified by affinity chromatography
Form & Buffer Supplied in lyophilized form

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by the end user

Storage & Safety

Storage Store at 4 deg C for short term storage. For long term storage aliquot and store at -20 deg C, avoid repeated freeze/thaw cycles.

General Information

Biological Significance INPPL1, a protein that in addition to the phosphatase domain contains an SH2 (src-homology domain 2) motif. INPPL1 is a member of the family of inositol triphosphate phosphatases. The INPPL1 gene is mapped on 11q13.4. Immunoblot analysis revealed that SHIP2 was widely expressed in fibroblast and nonhematopoietic tumor cell lines, unlike the SHIP protein, which was found only in cell lines of hematopoietic origin. Using human epithelial cell lines and primary human corneal and epidermal keratinocytes, Yu et al. showed that micro RNA-184 (MIR184) interfered with the ability of MIR205 to downregulate expression of SHIP2.SHIP2 may play a significant role in regulation of phosphatidylinositol 3-prime-kinase signaling by growth factors and insulin.

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Images

  • <div><font face=Calibri size=2>Immunohistochemical staining using INPPL1 antibody (70R-14287)</font></div>     | Immunohistochemistry of paraffin-embedded section of Human Intestinal, Cancer Tissue
  • <div><font face=Calibri size=2>Western Blot analysis using INPPL1 antibody (70R-14287)</font></div>     | Lane 1:Rat Heart Tissue Lysate, Lane 2:U87 Cell Lysate; Lane 3: HT1080 Cell Lysate; Lane 4: MCF-7 Cell Lysate

Availability: In stock

Price: $270.00
Size: 100 ug
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