Insulin Receptor alpha antibody (10R-8655)

Mouse monoclonal Insulin Receptor alpha antibody

Synonyms Monocloclonal Insulin Receptor alpha antibody, HIR A antibody, INSR alpha antibody, INSR alpha antibody, INSR antibody, Insulin receptor antibody, Insulin receptor subunit alpha antibody, IR antibody, Insulin Receptor alpha, Anti-Insulin Receptor alpha antibody, CD220 antibody, CD220 antigen antibody, HHF5 antibody
Specificity Alpha subunit of human insulin receptor
Cross Reactivity Human
Applications ELISA, IP, Neutralization, WB
Immunogen Insulin Receptor alpha antibody was raised in Mouse using highly purified insulin receptors (alpha-subunit) from human term placentas as the immunogen

Specifications

Host Mouse
Clone MA-20
Isotype IgG2b
Method of Purification Insulin Receptor alpha antibody was purified by affinity chromatography
Form & Buffer Supplied in 10 mM phosphate buffer (pH 7.4), 100 mM NaCl, and 0.1% sodium azide

Storage & Safety

Storage Store at -20 deg C, avoid freeze/thaw cycles

General Information

Biological Significance INSR binds insulin and has a tyrosine protein kinase activity. The short isoform has a higher affinity for insulin. The receptor mediates the metabolic functions of insulin. The receptor binding to insulin stimulates association of the receptor with downstream mediators including IRS1 and phosphatidylinositol 3'-kinase (PI3K). Defects in INSR are the cause of insulin resistance.

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Availability: In stock

Price: $295.00
Size: 50 ul
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