Insulin Receptor beta subunit antibody (10R-I137b)

Mouse monoclonal Insulin Receptor beta subunit antibody

Synonyms Monoclonal Insulin Receptor beta subunit antibody, Anti-Insulin Receptor beta subunit antibody, Insulin Receptor beta subunit antibody, Anti Insulin Receptor beta subunit antibody, Insulin Receptor (b-subunit) antibody, Insulin Receptor (b-subunit) antibody
Specificity Human
Cross Reactivity Monkey, mouse, rat
Applications ELISA, IHC-F, IHC-P, IP, WB
Immunogen Insulin receptor beta subunit antibody was raised in mouse using a 15-mer synthetic peptide corresponding to aa Tyr-KKNGILTLPRSNPS from the C-terminal of human insulin receptor beta-subunit as the immunogen.

Images

Immunohistochemical staining using Insulin Receptor beta subunit antibody (10R-I137b)

Formalin-fixed, paraffin-embedded rat brain stained with Insulin Receptor antibody using peroxidase-conjugate and AEC chromogen. Note staining of endothelial cells of capillaries.

Specifications

Host Mouse
Clone CT-3
Isotype IgG1
Method of Purification Insulin Receptor beta subunit antibody was purified by Protein G chromatography.
Molecular Weight 95 kDa (predicted detection band MW)
Form & Buffer Antibody purified from ascites fluid by protein G chromotography and supplied in 10mM PBS, pH 7.4, with 0.2% BSA and 0.09% NaN3.
Concentration 0.2 mg/ml

Usage & Assay Information

Usage Recommendations IHC-F: 1:50, IHC-P: 1:50, WB: 1-2 ug/ml

Storage & Safety

Storage Store at 4 deg C.
Biohazard Information This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling.

General Information

Biological Significance The human insulin receptor is a heterotetrameric membrane glycoprotein consisting of disulfide-linked subunits in a Beta- alpha- alpha-Beta configuration. The Beta-subunit (95 kDa) possesses a single transmembrane domain with tyrosine kinase acivity, whereas the alpha-subunit (135 kDa) is completely extracellular.

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Images

  • Immunohistochemical staining using Insulin Receptor beta subunit antibody (10R-I137b) | Formalin-fixed, paraffin-embedded rat brain stained with Insulin Receptor antibody using peroxidase-conjugate and AEC chromogen. Note staining of endothelial cells of capillaries.
  • Immunohistochemical staining using Insulin Receptor beta subunit antibody (10R-I137b) | Formalin-fixed, paraffin-embedded human placenta stained with Insulin Receptor antibody using peroxidase-conjugate and AEC chromogen. Note cell membrane staining of trophoblasts.

Availability: In stock

Price: $484.00
Size: 100 ug
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