IRF1 antibody (10R-1601)

Mouse monoclonal IRF1 antibody

Synonyms Monoclonal IRF1 antibody, Anti-IRF1 antibody, Interferon regulatory factor 1 antibody, IRF 1, IRF1, IRF-1 antibody, IRF 1 antibody, IRF-1 antibody, IRF-1, MAR antibody
Specificity Human IRF1
Cross Reactivity Human. Other species not studied
Applications Dot Blot, ICC
Immunogen IRF1 antibody was raised in mouse using recombinant Human Interferon Regulatory Factor 1 (Irf1)

Images

Immunofluorescent staining using IRF1 antibody (10R-1601)

Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.01% Triton-X100 in PBS. The cells were immunostained with anti-IRF1 antibody.

Specifications

Host Mouse
Clone 762C1a
Isotype IgG2b
Method of Purification IRF1 antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Form & Buffer Mouse monoclonal anti-humanIRF1 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1% bovine serum albumin (BSA) and 0.05% sodium azide (NaN3 ).
Concentration 100 ug/ml

Usage & Assay Information

Usage Recommendations ICC: 2-100 ug/ml

Storage & Safety

Storage Store at 2-8 deg C for up to one year. We recommend long term storage at -20 deg C. Avoid repeated freezing and thawing.
Biohazard Information This antibody solution contains sodium azide (NaN ) as a preservative. There is a potential hazard that NaN reacts with copper or lead to produce an explosive compound. For safe disposal, the vial has to be washed thoroughly with water. It is strongly adv

General Information

Biological Significance IRF1 encodes interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for doublestranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumorsuppressoion.

References
Add a Paper

Sorry, but there are no references currently for this product.

Reviews

You need to be logged in to write a review. Please login here

Sorry there are currently no reviews for this product

Images

  • Immunofluorescent staining using IRF1 antibody (10R-1601) | Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.01% Triton-X100 in PBS. The cells were immunostained with anti-IRF1 antibody.
  • Western Blot analysis of immunized recombinant protein using IRF1 antibody (10R-1601) | Left: IRF1 staining. Right: Coomassie Blue staining of immunized recombinant protein.

Availability: In stock

Price: $190.00
Size: 50 ug
OR
Shipping
View Our Distributors