IRF2 protein (His tag) (80R-1032)
Purified recombinant Human IRF2 protein
|Synonyms||IRF 2, IRF -2, IRF2, IRF 2 protein, Interferon regulatory factor 2 protein, DKFZp686F0244 protein, IRF2 protein, 1-113 aa His-tagged protein, Interferon regulatory factor-2 IRF 2., IRF -2 protein, IRF2 protein, IRF-2 protein|
Coomassie Blue stained SDS-PAGE of IRF2 protein (His tag) (80R-1032)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-113 amino acids: MGSSHHHHHH SSGLVPRGSH MPVERMRMRP WLEEQINSNT IPGLKWLNKE KKIFQIPWMH AARHGWDVEK DAPLFRNWAI HTGKHQPGVD KPDPKTWKAN FRCAMNSLPD IEEVKDKSIK KGNNAFRVYR MLP|
|Purity||> 95% pure|
|Molecular Weight||15 kDa ( 133 aa), confirmed by MALDI-TOF.|
|Form & Buffer||Supplied as a liquid in 20mM Tris, pH 8.0, containing 1mM DTT, and 10% glycerol.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||Interferon regulatory factor (IRF) 2 is a member of the interferon regulatory transcription factor family. IRF-2 is generally regarded as an oncoprotein. Structure of IRF1 and IRF2 are similar. However, its functions are different. IRF2 competitively inhibits the IRF1-mediated transcriptional activation of interferons alpha and beta, and presumably other genes that employ IRF1 for transcription activation. Recombinant human IRF2 was expressed in E. coli and purified by using conventional chromatography techniques.|
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