IRS4 antibody (20R-2929)

Rabbit polyclonal IRS4 antibody

Synonyms Polyclonal IRS4 antibody, Anti-IRS4 antibody, IRS4 antibody, insulin receptor substrate 4 antibody, 160 kDa phosphotyrosine protein antibody, BOS_25677 antibody, insulin receptor substrate 2-A antibody, insulin receptor substrate protein antibody, insulin receptor substrate-undetermined designation antibody, insulin receptor substrate-unique antibody, IRS1 antibody, irs2 antibody, irs2-a antibody, IRS-2-A antibody, IRS-4 antibody, phosphoprotein of 160 kDa antibody, pp160 antibody, py160 antibody, RP23-415G1.3 antibody, xIRS-u antibody
Cross Reactivity Human
Applications WB
Immunogen IRS4 antibody was raised in Rabbit using a synthetic target peptide as the immunogen

Images

Western Blot analysis using IRS4 antibody (20R-2929)

Specifications

Host Rabbit
Isotype IgG
Method of Purification IRS4 antibody was purified by Protein A affinity chromatography
Form & Buffer Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol

Usage & Assay Information

Usage Recommendations WB: 1:2000

Storage & Safety

Storage Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles

General Information

Biological Significance Insulin receptor substrate (IRS) proteins play a central role in maintaining basic cellular functions such as growth and metabolism through insulin/insulin like growth factor (IGF) signaling. Four members (IRS-1, IRS-2, IRS-3, IRS-4) of this family have been identified which differ in their subcellular distribution and interaction with SH2 domain proteins. After phosphorylation by activated receptors, these intracellular signaling molecules recruit various downstream effector pathways including phosphatidylinositol 3-kinase, tyrosine protein phosphatase SHPTP-2, and several smaller adapter molecules such as the growth factor receptor-binding protein Grb-2.

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Images

  • Western Blot analysis using IRS4 antibody (20R-2929) |

Availability: In stock

Price: $295.00
Size: 100 ul
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