ISG15 protein (His tag) (80R-3388)

Purified recombinant ISG15 protein (His tag)

Synonyms Interferon induced 15 kDa protein, Interferon induced 17 kDa protein, IP17 protein, Ubiquitin cross reactive protein, hUCRP protein, Ubiquitin like protein ISG15 protein, ISG 15 protein, ISG-15 protein
Species Human
Protein Type Recombinant
Applications ELISA, SDS-PAGE, WB

Images

Western blot analysis using ISG15 protein (His tag) (80R-3388)

Specifications

Expression System E.coli
Purity > 90% pure
Molecular Weight 24 kDa
Tag/Conjugate His tag
Form & Buffer Supplied in liquid form in 20mM Tris-Hcl, 0.5MNaCl, 10% glycerin (pH 8.0) and 200 mM Imidazole

Storage & Safety

Storage Store at 4 deg C in a working aliquot for 1 week. For long term storage, aliquot and freeze at -20 to -80 deg C, avoid repeat freeze/thaw cycles

General Information

Biological Significance ISG15, a ubiquitin-like protein that is conjugated to intracellular target proteins after IFN-alpha or IFN-beta stimulation. Its enzymatic pathway is partially distinct from that of ubiquitin, differing in substrate specificity and interaction with ligating enzymes. ISG15 conjugation pathway uses a dedicated E1 enzyme, but seems to converge with the Ub conjugation pathway at the level of a specific E2 enzyme. Targets include STAT1, SERPINA3G/SPI2A, JAK1, MAPK3/ERK1, PLCG1, EIF2AK2/PKR, MX1/MxA, and RIG-1. Deconjugated by USP18/UBP43.

References
Add a Paper

Sorry, but there are no references currently for this product.

Reviews

You need to be logged in to write a review. Please login here

Sorry there are currently no reviews for this product

Images

  • Western blot analysis using ISG15 protein (His tag) (80R-3388)

Availability: In stock

Price: $210.00
Size: 50 ug
OR
Shipping
View Our Distributors