ISL1 antibody (10R-2055)

Mouse monoclonal ISL1 antibody

Synonyms Monoclonal ISL1 antibody, Anti-ISL1 antibody, ISL-1 antibody, ISL 1 antibody, ISL1 transcription factor antibody, LIM antibody, ISL1, ISL 1, ISL-1, ISL 1 antibody, ISL-1 antibody
Cross Reactivity Human
Applications ELISA, IF, IHC, WB
Immunogen ISL1 antibody was raised in Mouse using a purified recombinant fragment of human ISL1 expressed in E. coli as the immunogen.

Images

Immunofluorescent staining using Western Blot analysis using ISL1 antibody (10R-2055) (ISL1 antibody)

Confocal immunofluorescence analysis of HEK293 cells trasfected with full-length ISL1-hIgGFc using ISL1 antibody (green). Blue: DRAQ5 fluorescent DNA dye.

Specifications

Host Mouse
Clone 1H9
Isotype IgG1
Form & Buffer Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.
Concentration 1.0 mg/ml

Usage & Assay Information

Usage Recommendations ELISA: 1:10,000, IF: 1:200-1:1000, IHC: 1:200-1:1000, WB: 1:500-1:2000

Storage & Safety

Storage Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance ISL1 is a member of the LIM/homeodomain family of transcription factors. It binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. It is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Islet-1 expression defines cardiac progenitor cell populations and is required for normal cardiac development and asymmetry. Mutations in this gene have been associated with maturity-onset diabetes of the young.

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Images

  • Immunofluorescent staining using Western Blot analysis using ISL1 antibody (10R-2055) (ISL1 antibody) | Confocal immunofluorescence analysis of HEK293 cells trasfected with full-length ISL1-hIgGFc using ISL1 antibody (green). Blue: DRAQ5 fluorescent DNA dye.
  • Western Blot analysis using ISL1 antibody (10R-2055) | Western Blot showing ISL1 antibody used against full-length ISL1 (aa1-349)-hIgGFc transfected HEK293 cell lysate (1).
  • Immunohistochemical staining using ISL1 antibody (10R-2055) | Immunohistochemical analysis of paraffin-embedded human lung cancer (left) and cervical carcinoma (right), showing nuclear localization using ISL1 antibody with DAB staining.

Availability: In stock

Price: $375.00
Size: 100 ul
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