ISOC2 protein (His tag) (80R-2990)
Purified recombinant ISOC2 protein (His tag)
|Synonyms||Isochorismatase domain-containing protein 2 protein, protein, ISOC 2 protein, ISOC-2 protein|
SDS-PAGE analysis of ISOC2 protein (His tag) (80R-2990)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||59-205 aa: MGSSHHHHHH SSGLVPRGSH MGSEQYPQGL GPTVPELGTE GLRPLAKTCF SMVPALQQEL DSRPQLRSVL LCGIEAQACI LNTTLDLLDR GLQVHVVVDA CSSRSQVDRL VALARMRQSG AFLSTSEGLI LQLVGDAVHP QFKEIQKLIK EPAPDSGLLG LFQGQNSLLH|
|Form & Buffer||Supplied in liquid form in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 10% glycerol|
Storage & Safety
|Storage||Store at 4 deg C for short term storage, for long term storage aliquot and store at -20 deg C or -70 deg C, avoid repeated freeze thaw cycles.|
|Biological Significance||HEPACAM2 is required during prometaphase for centrosome maturation. Following poly-ADP-ribosylation (PARsylation) by TNKS, this protein translocates from the Golgi apparatus to mitotic centrosomes and plays a key role in the formation of robust microtubules for prompt movement of chromosomes.|
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