ITGB3BP protein (His tag) (80R-2763)

Purified recombinant ITGB3BP protein (His tag)

Synonyms Cntromere protein R isoform 1 protein, CENP-R protein, CENPR protein, HSU37139 protein, NRIF3 protein, TAP20 protein, ITGB3BP
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

SDS-PAGE analysis of ITGB3BP protein (His tag) (80R-2763)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 1-216 aa: MGSSHHHHHH SSGLVPRGSH MGSMPFAPVA QARVQWHDFR SLQHLLPAFK RFSCLSLGSS WDYSVKRSLK LDGLLEENSF DPSKITRKKS VITYSPTTGT CQMSLFASPT SSEEQKHRNG LSNEKRKKLN HPSLTESKES TTKDNDEFMM LLSKVEKLSE EIMEIMQNLS SIQALEGSRE LENLIGISCA SHFLKREMQK TKELMTKVNK QKLFEKSTGL PHKASRHLDS YEFLKAILN
Expression System E.coli
Purity > 90% pure
Molecular Weight 27.1 kDa
Tag/Conjugate His tag
Form & Buffer Supplied in liquid form in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 10% glycerol
Concentration 500 ug/ml

Storage & Safety

Storage Can be stored at 4 deg C short term (1-2 weeks). For long term storage, aliquot and store at -20 deg C or -70 deg C. Avoid repeated freezing and thawing cycles.

General Information

Biological Significance Cntromere protein R isoform 1, also known as ITGB3BP1, is a widely expressed protein that contains a DD1 or RepD1 domain and an LXXLL motif. Induced by estrogen, ITGB3BP1 is believed to function as a nuclear receptor coactivator. It also associates with the CENP-A-CAD complex which is involved in mitotic progression, the assembly of kinetochore proteins and chromosome segregation. It acts as a transcriptional corepressor via its interaction with the NFKB1 NF-kappa-B subunit, possibly by interfering with the transactivation domain of NFKB1. Recombinant human ITGB3BP1 protein, fused to His-tag at N-terminus, was expressed in E.coli.

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Images

  • SDS-PAGE analysis of ITGB3BP protein (His tag) (80R-2763) | Figure annotation denotes ug of protein loaded and % gel used.
  • SDS-PAGE analysis of ITGB3BP protein (His tag) (80R-2763) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: $270.00
Size: 20 ug
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