ITI H4 antibody (10R-8463)

Mouse monoclonal ITI H4 antibody

Synonyms Monoclonal ITI H4 antibody, Anti-ITI H4 antibody, ITIH4 antibody, inter-alpha-trypsin inhibitor heavy chain family antibody, member 4 antibody, BOS_20961 antibody, GP120 antibody, H4P antibody, IHRP antibody, inter-alpha (globulin) inhibitor H4 (plasma Kallikrein-sensitive glycoprotein) antibody, inter-alpha-inhibitor H4 heavy chain antibody, inter-alpha-inhibitor heavy chain 4 antibody, inter-alpha-trypsin inhibitor family heavy chain-related protein antibody, inter alpha-trypsin inhibitor antibody, heavy chain 4 antibody, inter-alpha-trypsin inhibitor heavy chain H4 antibody, inter-alpha-trypsin inhibitor antibody, heavy chain-like antibody, 1 antibody, Itih-4 antibody, ITI-HC4 antibody, ITI heavy chain H4 antibody, ITIHL1 antibody, major acute phase protein antibody, MAP antibody, PK120 antibody, PK-120 antibody, plasma kallikrein-sensitive glycoprotein 120 antibody, PRO1851 antibody, RP23-205O23.1 antibody
Cross Reactivity Human
Applications ELISA, IHC-P, WB
Immunogen ITI H4 antibody was raised in Mouse using a protein purified from Human plasma as the immunogen

Images

Western Blot analysis using ITI H4 antibody (10R-8463)

Specifications

Host Mouse
Clone 45A12
Isotype IgG1 kappa
Method of Purification ITI H4 antibody was purified by ammonium sulfate precipitation
Form & Buffer Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol

Usage & Assay Information

Usage Recommendations WB: 1: 2000

Storage & Safety

Storage Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles

General Information

Biological Significance The inter-alpha-trypsin inhibitor (ITI) family, a typical and classical example for protein-glycosaminoglycanprotein (PGP) complexes, occurs constitutively in plasma at relatively high concentrations and is a result of alternate combinations of three kinds of heavy chains with a common light chain, the bikunin proteoglycan. Bikunin has two proteinase inhibitor domains and belongs to the Kunitz-type protease inhibitor family; it displays an inhibitory activity against trypsin, leukocyte elastase and plasmin. The heavy chains do not have any protease inhibitory properties but have the capacity to interact in vitro and in vivo with hyaluronic acid and this binding promotes the stability of the extra-cellular matrix. The ITI protein family is suspected of playing a key role in the extra-cellular matrix biology.

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Images

  • Western Blot analysis using ITI H4 antibody (10R-8463) |

Availability: In stock

Price: $295.00
Size: 100 ul
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