Itraconazole Reference Standard (50R-R51211)
Itraconazole chemical reference substance
|Synonyms||Itraconazole Reference Standard, Itraconazole RS, RS for Itraconazole, Itraconazole (powder)|
|Form & Buffer||Supplied as a powder.|
|Biological Significance||Itraconazole is a triazole antifungal agent that is prescribed to patients with fungal infections. The drug may be given orally or intravenously. The mechanism of action of itraconazole is the same as the other azole antifungals: it inhibits the fungal cytochrome P450 oxidase-mediated synthesis of ergosterol. Because of its ability to inhibit cytochrome P450 3A4 CC-3, caution should be used when considering interactions with other medications.|
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