JAK2 protein (His tag) (80R-3620)
Purified recombinant JAK2 protein (His tag)
|Synonyms||Janus kinase 2 (a protein tyrosine kinase) protein, JTK10 protein, JAK 2 protein, JAK-2 protein|
Coomassie blue stained SDS-PAGE of JAK2 protein (His tag) (80R-3620)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1014-1132 aa: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMGE SPIFWYAPES LTESKFSVAS DVWSFGVVLY ELFTYIEKSK SPPAEFMRMI GNDKQGQMIV FHLIELLKNN GRLPRPDGCP DEIYMIMTEC WNNNVNQRPS FRDLALRVDQ IRDNMAG|
|Purity||> 95% pure|
|Method of Purification||JAK2 protein was purified by using conventional chromatography techniques|
|Molecular Weight||18.1 kDa|
|Form & Buffer||Supplied in liquid form in 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M Urea|
Storage & Safety
|Storage||Can be stored at 4 deg C short term (1-2 weeks). For long term storage, aliquot and store at -20 deg C or -70 deg C. Avoid repeated freezing and thawing cycles.|
|Biological Significance||JAK2 is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.|
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