JDP2 protein (His tag) (80R-2773)

Purified recombinant JDP2 protein (His tag)

Synonyms Jun dimerization protein 2 protein, JUNDM2 protein, JDP2, JDP 2, JDP-2
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

SDS-PAGE analysis of JDP2 protein (His tag) (80R-2773)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 1-163 aa: MGSSHHHHHH SSGLVPRGSH MGSHMMPGQI PDPSVTTGSL PGLGPLTGLP SSALTVEELK YADIRNLGAM IAPLHFLEVK LGKRPQPVKS ELDEEEERRK RRREKNKVAA ARCRNKKKER TEFLQRESER LELMNAELKT QIEELKQERQ QLILMLNRHR PTCIVRTDSV KTPESEGNPL LEQLEKK
Expression System E.coli
Purity > 90% pure
Molecular Weight 21.2 kDa
Tag/Conjugate His tag
Form & Buffer Supplied in liquid form in 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 50% glycerol, 1mM DTT, 1mM EDTA, 250mM imidazole
Concentration 250 ug/ml

Storage & Safety

Storage Can be stored at 4 deg C short term (1-2 weeks). For long term storage, aliquot and store at -20 deg C or -70 deg C. Avoid repeated freezing and thawing cycles.

General Information

Biological Significance Jun dimerization protein 2, also known as JDP2, is a component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. This protein is involved in a variety of transcriptional responses associated with AP-1 such as UV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. JDP2 can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN. It may control transcription via direct regulation of the modification of histones and the assembly of chromatin. Recombinant human JDP2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

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Images

  • SDS-PAGE analysis of JDP2 protein (His tag) (80R-2773) | Figure annotation denotes ug of protein loaded and % gel used.
  • SDS-PAGE analysis of JDP2 protein (His tag) (80R-2773) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: $270.00
Size: 10 ug
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