KARS antibody (10R-1990)

Mouse monoclonal KARS antibody

Synonyms Monoclonal KARS antibody, Anti-KARS antibody, Lysyl-tRNA Synthetase antibody, Monoclonal KARS antibody, Anti-KARS antibody, Lysyl-tRNA Synthetase antibody
Cross Reactivity Human
Applications ELISA, WB
Immunogen KARS antibody was raised in Mouse using a purified recombinant fragment of KARS(aa90-174) expressed in E. coli as the immunogen.

Images

Immunohistochemical staining using KARS antibody (10R-1990)

Immunohistochemical analysis of paraffin-embedded human Tonsil tissues using KARS antibody

Specifications

Host Mouse
Clone 8G12C1
Isotype IgG1
Form & Buffer Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.
Concentration 1.0 mg/ml

Usage & Assay Information

Usage Recommendations ELISA: 1:10,000, WB: 1:500-1:2000

Storage & Safety

Storage Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis.

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Images

  • Immunohistochemical staining using KARS antibody (10R-1990) | Immunohistochemical analysis of paraffin-embedded human Tonsil tissues using KARS antibody
  • Western Blot analysis using KARS antibody (10R-1990) | Western Blot showing KARS antibody used against truncated Trx-KARS recombinant protein (1), truncated MBP-KARS (aa90-174) and full length KARS (aa1-188) transfected CHO-K1 cell lysate (3).
  • Immunohistochemical staining using KARS antibody (10R-1990) | Immunohistochemical analysis of paraffin-embedded human cervical carcinoma, showing cytoplasmic localization with DAB staining using KARS antibody.

Availability: In stock

Price: $345.00
Size: 100 ul
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