Keratin K18 antibody (10R-2397)

Mouse monoclonal Keratin K18 antibody

Synonyms Monoclonal Keratin K18 antibody, Anti Keratin K18 antibody, Keratin K 18, Keratin K-18, Cytokeratin 18 antibody, Keratin K18, Keratin K-18 antibody, Keratin K 18 antibody
Cross Reactivity To be determined by the end user
Applications User optimized

Specifications

Host Mouse
Clone Ks18.04
Form & Buffer Supplied in liquid form

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by end user

Storage & Safety

Storage Store at 2-8 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Keratin 18 is a type I cytokeratin. It is, together with its filament partner keratin 8, perhaps the most commonly found products of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene. Keratin 18 is often used together with keratin 8 and keratin 19 to differentiate cells of epithelial origin from hematopoietic cells in tests that enumerate circulating tumor cells in blood.

References
Add a Paper

Shuang Cuia, Louis M. Capeccia, Randolph P. Matthews

Disruption of planar cell polarity activity leads to developmental biliary defects

Developmental Biology

Volume: 351 Issue: 2 Page: 229-241 DOI: 10.1016/j.ydbio.2010.12.041

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