Keratin K18 antibody (10R-2406)

Mouse monoclonal Keratin K18 antibody

Synonyms Monoclonal KRT18 antibody, Anti-KRT18 antibody, Keratin K-18 antibody, Keratin K 18 antibody, Keratin D antibody, Cytokeratin 18 antibody, Cytokeratin endo B antibody, CYK18 antibody, Keratin type I cytoskeletal 18 antibody, Cell proliferation inducing protein 46 antibody, Keratin K-18, Keratin K 18, K18 antibody, Cell proliferation inducing gene 46 protein antibody, Keratin K18, CK 18 antibody, Keratin 18 antibody, Kerd antibody
Specificity Human keratin K18
Cross Reactivity Bovine
Applications ELISA, IHC, WB
Immunogen Keratin K18 antibody was raised in mouse using Cytoskeletal preparation from human tumor cell line MCF-7 as the immunogen.

Specifications

Host Mouse
Clone Ks18.5
Isotype IgG1
Form & Buffer Supplied in liquid form, contains 0.09% NaN3

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by end user

Storage & Safety

Storage Store at 2-8 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Keratin 18 is a type I cytokeratin. It is, together with its filament partner keratin 8, perhaps the most commonly found products of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene. Keratin 18 is often used together with keratin 8 and keratin 19 to differentiate cells of epithelial origin from hematopoietic cells in tests that enumerate circulating tumor cells in blood.

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Price: $212.00
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