KGF protein (30R-AK002)

Purified recombinant Human KGF protein

Synonyms Keratinocyte Growth Factor protein, HBGF-7 protein, Fibroblast Growth Factor-7 protein
Species Human
Protein Type Recombinant
Applications User optimized

Specifications

Residues Region of KGF protein corresponding to amino acids MCNDMTPEQM ATNVNCSSPE RHTRSYDYME GGDIRVRRLF CRTQWYLRID KRGKVKGTQE MKNNYNIMEI RTVAVGIVAI KGVESEFYLA MNKEGKLYAK KECNEDCNFK ELILENHYNT YASAKWTHNG GEMFVALNQK GIPVRGKKTK KEQKTAHFLP MAIT.
Expression System E.coli
Purity > 95% pure
Molecular Weight 18.9 kDa
Form & Buffer Lyophilized from 15mM Na3PO4 with 0.25 M NaCl, pH7.0. Reconstitute in PBS to a concentration of 0.5-1.0 mg/ml.

Usage & Assay Information

Bioactivity The ED50 as determined by the dose-dependent stimulation of thymidine uptake by KGF-responsive BaF3 cells is approximately 10 ng/ml, corresponding to a specific activity of approximately 1 x 10^5 units/mg.

Storage & Safety

Storage Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Endotoxin Levels Endotoxin level is less than 0.1 ng per ug (1 EU/ug).

General Information

Biological Significance Keratinocyte Growth Factor (KGF/FGF7) is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of variety of tissues, by promoting cellular proliferation and differentiation. KGF/FG-7 is a mitogen factor specific for epithelial cells and keratinocytes and signals through FGFR 2b. KGF/FGF7 plays a role in kidney and lung development, angiogenesis, and wound healing.

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Availability: In stock

Price: $225.00
Size: 10 ug
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