KISS1 protein (30R-1202)
Purified recombinant Human KISS1 protein
|Synonyms||KiSS-1 metastasis-suppressor protein, Kisspeptin-1 protein, KISS-1 protein, MGC39258 protein, ' ', KISS 1, KiSS-1 metastasis-suppressor protein, KISS-1, METASTIN protein, KISS 1 protein, KISS1 protein, KISS1|
Coomassie Blue stained SDS-PAGE of KISS1 protein (30R-1202)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-120 amino acids: MEPLEKVASV GNSRPTGQQL ESLGLLAPGE QSLPCTERKP AATARLSRRG TSLSPPPESS GSPQQPGLSA PHSRQIPAPQ GAVLVQREKD LPNYNWNSFG LRFGKREAAP GNHGRSAGRG|
|Purity||> 90% pure|
|Molecular Weight||12.6 kDa (120 aa), confirmed by MALDI-TOF. (Molecular weight on SDS-PAGE will appear higher)|
|Form & Buffer||Supplied as a liquid in 20mM Tris, pH 8.0, containing 1mM DTT, and 10% glycerol.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||KiSS-1 metastasis-suppressor (KISS1) is a metastasis suppressor gene that suppresses metastases of melanomas and breast carcinomas without affecting tumorigenicity. The metastasis suppressor properties may be mediated in part by cell cycle arrest and induction of apoptosis in malignant cells. Expression of KiSS1 has been localized to specific regions of the hypothalamus in many species and is regulated by gonadal steroids and across the estrous cycle. Recombinant KISS1 protein was expressed in E. coli and purified by using conventional chromatography techniques.|
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